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BIOINF-547

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Probailistics Modeling in Bioinformatics - 3 Credits

The course will be about probabilistic models of proteins and nucleic acids, and their uses in molecular biology. The core of the course will be the analysis of sequences and its biological applications such as the searching of large databases for optimal comparisons or homologies of sequences (DNA nucleotide sequences or amino acid sequences for proteins), location of genes on a string of DNA, estimation of phylogenetic trees, structural motif recognition for proteins and RNA. Guest lecturers will address the class on topics from the pharmaceutical industry, DNA physics and chromatin structure.

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